Program 2025 – Shanghai

PROGRAM - 5th International Keloid Symposium - Shanghai, China

Time

Speaker

Title

DAY 1
Friday June 6, 2025

08:00 - 08:30
Registration and Morning Coffee
08:30 - 09:00
Welcome to Shanghai, &
Opening of the 5th International Keloid Symposium
Session 1
09:00 - 10:00
Chair: Weil Liu, MD, PhD
Co-Chair: Michael H Tirgan, MD
Open Forum: Understanding the True Nature of Keloid Disorder: Toward a Rational and Effective Therapeutic Strategy
09:00 - 10:00
All Invited Speakers

Panel Discussion and Q/A

10:00-10:30

Coffee Break

Session 2
10:30 - 12:30
Chair: Xiaoli Wu, MD, PhD
Co-Chair: Frank Nissen, MD, PhD
What’s New in Keloid Pathophysiology and Treatment: A 2025 Update.
Frank Nissen, MD, PhD
Keloid Research and Therapy: A Worldwide Update on Scientific and Clinical Progress
Wei Liu, MD, PhD
An Integrative Approach to Unravel Keloid Pathogenesis and Optimize Therapeutic Outcomes.
Xiaoli Wu, MD, PhD
Innovative Advances in Keloid Therapy: Breakthrough Techniques from China.
Michael H Tirgan, MD
Changing the Paradigm in Keloid Treatment: An Oncologist’s Insights.

Panel Discussion and Q/A

12:30-13:30

Lunch Break

Special Session
12:45 - 13:15
Keloid Research Foundation
Keloid Nomenclature Working Group: Aiming to Harmonize Definitions and to Adopt Standard Nomenclature. This Session is Open to all Participants. 19th Floor Conference Room.
Session 3
13:30 - 15:00
Akash Gujan, PhD
Co-Chair: Bingrong Zhou MD, PhD
Evidence-Based Non-Surgical Strategies for Keloid Treatment
Akash Gujan, PhD
Leveraging Machine Learning Using Clinical Data to Predict Response to Intralesional Steroids in Keloid Patients.
Xiaoli Wu, MD, PhD
LCR Technique for Treatment of Keloids
Tony Chan, MD
Intralesional Cryotherapy for Treatment of Keloids.
Bingrong Zhou, MD, PhD
Novel Needle-Type Electrocoagulation and Combination Pharmacotherapy: Basic and Clinical Studies on Efficacy and Safety in Treating Keloids
Joanne Smith, OT
Innovative Compression Technology for Ear Keloids: Reducing Recurrence Rates Effectively.
Ka-Wing Wong, MS, OT
Innovative Application of Scanning, Printing and Pressure Sensors Technologies to Improve Patient Experience in Auricular Keloids Management.
Panel Discussion and Q/A
15:00 - 15:15
Wei Liu, MD, PhD
Industry-Sponsored Presentations - Alma Laser for Scar Treatment

15:15 – 15:30

Coffee Break

Session 4

15:30 – 17:30

Chair: Youbin Wang, MD
Co-Chair: Lamont Jones, MD, MBA
Rethinking Keloid Surgery: Toward Predictable and Long-Lasting Outcomes
Youbin Wang, MD, PhD
Facial Keloid Treatment with Keloid Subepidermal Vascular Network Fap (KSVNFs): A Long-Term Follow-up Study
Jinglong Cai, MD
Treatment Methods and Efficacy in Pediatric Keloids.
Ioannis Goutos, FRCSEd (Plast)
Surgical Management of Large Volume Keloids.
Renliang He, MD
Trephination Technique in Treating Keloids.
Mingming Pan, MS
Retrospective review of a single tertiary care medical center’s surgical keloid population over a 30-year period.
Chunmei Wang, MD, PhD
From Planning to Practice: Key Surgical Techniques in Personalized Keloid Management.
Panel Discussion and Q/A
Reception
17:30 - 19:00
Everyone is Invited
Dinner
19:00 - 21:00
Dinner for Speakers and Registered Attendee

Time

Speaker

Title

DAY 2
Saturday June 7, 2025

08:00 - 08:30
Registration and Morning Coffee
Session 1
08:30 - 10:30
Chair: Yixin Zhang, MD, PhD
Co-Chair: Nanze Yu, MD, PhD
Molecular and Cellular Insights into Keloid Formation

Yixin Zhang, MD

Molecular and Immune-Mechanism of Keloid Development.

Mark Fear, PhD

Understanding the Mechanisms of Keloid Recurrence and Exploring Novel Therapeutic Options.

Zhilian Qin, MD

Inhibition ENO1 Expression Targets the Glycolytic and Lactylation to Regulate Keloid Fibroblast Function.

Chenyu Huang, MD

Asporin Inhibits Collagen Matrix-Mediated Intercellular Mechano-Communications Between Fibroblasts during Keloid Progression.

Nanze Yu, MD, PhD

Understanding and Clinical Practice of Vascular Abnormalities in Keloid Disease.

Chengcheng Deng, PhD

BMP2-Induced Adam12+ Fibroblasts Dictate Skin Scarring and Fibrosis.

Panel Discussion and Q/A

10:15 - 10:30
Xiaoli Wu, MD, PhD
Industry Sponsored Presentation : Application of Wound Pressure Reduction Device in the Treatment of Keloids

10:30-10:45

Coffee Break

Session 2
10:45 - 12:30
Chair: John Glees, MD
Co-Chair: Jonathan Tsao, MD
Evidence-Based Radiotherapy in Management of Keloids

Jonathan Tsao, MD

Adjuvant Radiotherapy for the Treatment of Keloids.

Henry Weatherburn, PhD

A Data-Based Approach to a Keloid Post-Excisional Radiotherapy Treatment (PERT) Pathway.

John Glees, MD, FRCR, DMRT

Case Studies of Patient Outcomes of Re-Treatment of Recurrent Keloid Tumours by Fractionated Superficial X-Ray Radiotherapy

Zhongling Qiu, MD

Isotope Therapy to Prevent Post-Surgical Keloid Recurrence.

Hui Yao, MD

Adjuvant, Post-Operative Electron Beam Irradiation in Treatment of Keloids.

Xu Jinhui, MD

Industry Sponsored Presentation: Superficial X-Ray Irradiation for Keloid Treatment.

Panel Discussion and Q/A

12:30-13:30

Lunch Break

Special Session
12:45 - 13:15
Keloid Research Foundation
Harmonizing Clinical Endpoints: Response Criteria Working Group for Keloid Trials. - 19th Floor Conference Room.
Session 3
13:30 - 15:30
Chair: Xiaodong Chen, MD, PhD
Co-Chair: Henry Weatherburn, PhD
Surgical Treatment of Keloids in Conjunction with Radiation Therapy

Jinglong Cai, PhD

Can Keloids Be Cured? Evidence-Based Criteria for Patient Selection and Treatment

Henry Weatherburn, PhD

A 15 Year Single Centre Audit of the Outcome of Fractionated Superficial X-Ray Radiotherapy Treatment of Recurrent Keloid Tumours.

Kamalendu Malakar, MD, PhD

Optimizing Radio-Tolerance of Skin Graft Following Keloidectomy

Wei Liu, MD, PhD

Use of Punch Biopsy Procedure to Treat Wide-Spread Keloids.

Xiaomei Han, MD

Full-Process Management of Auricular Keloids: The Role of the Innovative ABC Surgical Technique in a Multidisciplinary Treatment Framework.

Xiaodong Chen, MD, PhD

Nucleoresection Combined with Punch Extraction and Radiation Therapy: a Keloid Surgical Technique Worth Promoting.

Panel Discussion and Q/A

15:00 – 15:15

Wenbo Wang, MD, PhD

Industry Sponsored Presentation: Application of Hyaluronic Acid and its Functional Technology in the Field of Scars.

15:15 – 15:30

Coffee Break

Session 4

15:30 – 17:30

Chair: Patricia Yap, MD
Co-Chair: Cecilia Li, MD, PhD
Advances in Non-Surgical Management of Keloid Patients

Cecilia Li, MD, PhD

Novel Concept and Clinical Practice of Keloid Pressure Therapy

Eva Chintia Yessica Manalu, BMedSc

Bridging a Therapeutic Gap: Hydrocortisone Occlusion Dressing after Keloid Excision in Indonesia’s National Referral Hospital – A Case Series.

Patricia Yap, MD

Keloid Tumors and Telemedicine – a Patient’s Journey.

Haiguang Zhao, MD, PhD

Combining Laser and Intralesional Therapies in Treating Keloids.

Bingrong Zhou, MD, PhD

Novel Needle-Type Electrocoagulation and Combination Pharmacotherapy: Basic and Clinical Studies on Efficacy and Safety in Treating Keloids.

17:00 - 17:30
Panel Discussion and Q/A
Reception
18:00 - 19:00
Everyone is Invited
Dinner
19:00 - 22:00
Everyone is Invited

Time

Speaker

Title

DAY 3
Sunday June 8, 2025

08:00 - 08:30
Registration and Morning Coffee
Session 1
08:30 - 10:30
Chair: Frank Nissen, MD, PhD
Co-Chair: Dan Deng, MD, PhD
Complexities in Keloid Disorder: Clinical Realities Across Age Groups

Michael H. Tirgan, MD

Pediatric Keloids: Case Review, Clinical Patterns, and Treatment Recommendations.

Dan Deng, MD, PhD

Pediatric Keloid Experience and Treatment at Shanghai Children’s Medical Center

Wei Liu, MD, PhD

Therapeutic Principles for Pediatric Keloids.

Xiqiao Wang, MD

Microbiome Dysbiosis Dominated by Rhodococcus Occurs in Keloids

Juliette Louter

How do I Deal with the Keloid Disease: a Qualitative Study Exploring Coping Strategies in a Multicultural Adult Patient Population.

Lina Ndjock Mbolong, MD

Understanding the Emotional Impact of Living with Keloids.

Panel Discussion and Q/A

Special Session
10:30 - 10:45
Wei Liu, MD, PhD
Industry Sponsored Presentation: Application of Silicone Products in Scar Management.

10:45-11:00

Coffee Break

Special Session
11:00 - 11:30
Lamont Jones, MD, MBA
The Annual Jouni Uitto, MD, PhD International Visiting Professorship and Lecture in Molecular Dermatology Clinical Biomarkers: The Future of Keloid Disease's Diagnosis and Treatment.
Session 2
11:30 - 12:30
Chair: Jonathan Tsao, MD
Co-Chair: Chunhui Xie, MD, PhD
Abstract Presentation - Clinical Science

Chunhui Xie, MD

Application of Core Excision in the Treatment of Keloids.

Yan Hao, MD

Clinical Observation of Subepidermal Vascular Network Flaps in Keloid Patients.

Bing Li, MD, PhD

Surgery Approaches and Experiences for Keloid Treatment and the Adjunctive Therapy.

Wenbo Wang, MD, PhD

An Innovative Single-Stage Approach of High-Tension Keloid Excision and Reconstruction Using Acellular Dermal Matrix and Epidermal Skin Grafting

Michael H Tirgan, MD

Cartesian Model of Clinical Behavior of Keloid Disorder.

Panel Discussion and Q/A

12:30-13:30

Lunch Break

Special Session
12:45 - 13:15
Keloid Research Foundation
Bridging Progress: What We Learned in Shanghai and What Lies Ahead - Strategic Planning for Amsterdam 2026 - 19th Floor Conference Room.
Session 3
13:30 - 15:00
Chair: Frank Nissen, MD, PhD
Co-Chair: Lamont Jones, MD, PhD
Abstract Presentation - Basic Science

Akash Gunjan, PhD

Rationale Based Repurposing of FDA-Approved Agents for Keloid Management: An in Vitro Study.

Lian Zhang, MD

Integrated Multi-Omics Unveils the Epigenetic Landscape in the Pathogenesis of Keloid.

Tianhao Li, PhD

TWIST1 Promote TGF-β Receptor I in Keloid Fibroblasts via Regulating the Stability of MEF2A.

Tianhao Li, PhD

Integrated Analysis of TWIST1 in Keloid Pathogenesis: Single-Cell Transcriptomics Reveals Fibroblast Heterogeneity and a Novel MEF2A-TBR1 Regulatory Axis.

Mengjie Shan, MD, PhD

Multi-Omics Analyses Reveal Bacteria and Catalase Associated with Keloid Disease.

Yixin Sun, MD, PhD

Single-Cell RNA Sequencing Revealed Key Factors of EMT to Promote Fibroblast Activation and Immune Infiltration in Keloid

Junxian Wen, PhD Candidate

Endothelial Dysfunction in Keloid Formation and Therapeutic Insights.

Zonan Chen, MD, PhD

Keloids and Inflammation: The Critical Role of IL-33 in Epidermal Changes.

Panel Discussion and Q/A

15:15 – 15:30

Coffee Break

Session 4

15:30 – 17:00

Chair: Wei Liu, MD, PhD
Co-Chair: Michael Tirgan, MD
Abstract Presentation - Basic Science

Michael Tirgan, MD

Contact Cryotherapy in Treatment of Keloid Lesions: Indications and Case Studies.

Yingrou Tan, PhD

Dual siRNAs Nanoplex Targeting IL-4RA and SPARC Enhance Collagen Reduction in IL-4 Activated Skin Fibroblasts.

Qiannan Li, MD, PhD

Tissue Chondrification and Ossification in Keloids: Report of Five Cases.

Xinwen Kuang, MD, PhD candidate

Multi-Dimensional Effects of Hydrogen-Rich Materials on Wound Healing and Alleviating Skin Fibrosis.

Zhijin Li, PhD

Unraveling the Vascular Tapestry: Endothelial Dysfunction in Keloid Formation and Therapeutic Insights.

Shuo Li, MD, PhD

Establishment of a Deep Learning-Based Automated Segmentation and Blood Perfusion Prediction System for Keloids.

Panel Discussion and Q/A
17:00 - 17:15
Closing Remarks
Reception
17:00 - 18:30
Everyone is Invited