Program 2025 – Shanghai

PROGRAM - 5th International Keloid Symposium - Shanghai, China

Time

Speaker

Title

DAY 1
Friday June 6, 2025

08:00 - 08:30
Registration and Morning Coffee
08:30 - 09:00
Welcome to Shanghai, &
Opening of the 5th International Keloid Symposium
Session 1
09:00 - 10:30
Chair: Weil Liu, MD, PhD
Co-Chair: Michael H Tirgan, MD
Open Forum: Understanding the True Nature of Keloid Disorder: Toward a Rational and Effective Therapeutic Strategy
09:00 - 10:00
All Invited Speakers

Panel Discussion and Q/A

10:00-10:30

Coffee Break

Session 2
10:30 - 12:20
Chair: Xiaoli Wu, MD, PhD
Co-Chair: Frank Nissen, MD, PhD
What’s New in Keloid Pathophysiology and Treatment: A 2025 Update.
Frank Nissen, MD, PhD
Keloid Research and Therapy: A Worldwide Update on Scientific and Clinical Progress
Wei Liu, MD, PhD
An Integrative Approach to Unravel Keloid Pathogenesis and Optimize Therapeutic Outcomes.
Xiaoli Wu, MD, PhD
Innovative Advances in Keloid Therapy: Breakthrough Techniques from China.
Michael H Tirgan, MD
Changing the Paradigm in Keloid Treatment: An Oncologist’s Insights.

Panel Discussion and Q/A

12:20-13:30

Lunch Break

Special Session
12:30 - 12:45
Industry-Sponsored Presentations
TBD
Special Session
12:45 - 13:00
Industry-Sponsored Presentations
TBD
Special Session
13:00 - 13:30
Keloid Research Foundation
Keloid Nomenclature Working Group: Aiming to Harmonize Definitions and to Adopt Standard Nomenclature. This Session is Open to all Participants.
Session 3
13:30 - 15:00
Chair: Michael Tirgan, MD
Co-Chair: Cecilia Li, MD
Clinical Session 1: Evidence-Based Non-Surgical Strategies for Keloid Treatment
Qi Yin, MD
KECORT Study: An International e-Delphi Study on the Treatment of KEloids Using Intralesional CORTicosteroids in Clinical Practice.
Akash Gujan, PhD
Leveraging Machine Learning Using Clinical Data to Predict Response to Intralesional Steroids in Keloid Patients.
Cecilia Li, MD
Novel Concept and Clinical Practice of Keloid Pressure Therapy
Tony Chan, MD
Intralesional Cryotherapy for Treatment of Keloids.
Patricia Yap, MD
Keloid Tumors and Telemedicine - a Patient’s Journey.
Bingrong Zhou, MD, PhD
Novel Needle-Type Electrocoagulation and Combination Pharmacotherapy: Basic and Clinical Studies on Efficacy and Safety in Treating Keloids
Joanne Smith, OT
Innovative Compression Technology for Ear Keloids: Reducing Recurrence Rates Effectively.
Ka-Wing Wong, MS, OT
Innovative Application of Scanning, Printing and Pressure Sensors Technologies to Improve Patient Experience in Auricular Keloids Management.
Panel Discussion and Q/A

15:00 – 15:30

Coffee Break

Session 4

15:30 – 17:30

Chair: Youbin Wang, MD
Co-Chair: Lamont Jones, MD, MBA
Clinical Session 2: Keloid Surgery – Indications, Techniques, and Outcome Optimization
Youbin Wang, MD, PhD
Facial Keloid Treatment with Keloid Subepidermal Vascular Network Fap (KSVNFs): A Long-Term Follow-up Study
Xiongdong Chen, MD
Nucleoresection Combined with Punch Extraction: a Keloid Surgical Technique Worth Promoting.
Ioannis Goutos, FRCSEd (Plast)
Surgical Management of Large Volume Keloids.
Renliang He, MD
Trephination Technique in Treating Keloids.
Mingming Pan, MS
Retrospective review of a single tertiary care medical center’s surgical keloid population over a 30-year period.
Chunmei Wang, MD, PhD
From Planning to Practice: Key Surgical Techniques in Personalized Keloid Management.
Panel Discussion and Q/A
Reception
17:30 - 19:00
Everyone is Invited
Dinner
19:00 - 21:00
Dinner for all attendees. Everyone is Invited

Time

Speaker

Title

DAY 2
Saturday June 7, 2025

08:00 - 08:30
Registration and Morning Coffee
Session 1
09:00 - 10:30
Chair: Yixin Zhang, MD, PhD
Co-Chair: Nanze Yu, MD, PhD
Research Session 1: New Insights from Basic Science in Keloid Research

Yixin Zhang, MD

Molecular and Immune-Mechanism of Keloid Development.

Mark Fear, PhD

Understanding the Mechanisms of Keloid Recurrence and Exploring Novel Therapeutic Options.

Zhilian Qin, MD

Inhibition ENO1 Expression Targets the Glycolytic and Lactylation to Regulate Keloid Fibroblast Function.

Chenyu Huang, MD

Asporin Inhibits Collagen Matrix-Mediated Intercellular Mechano-Communications Between Fibroblasts during Keloid Progression.

Nanze Yu, MD, PhD

Understanding and Clinical Practice of Vascular Abnormalities in Keloid Disease.

Panel Discussion and Q/A

10:30-10:45

Coffee Break

Session 2
10:45 - 12:30
Chair: John Glees, MD
Co-Chair: Jonathan Tsao, MD
Clinical Session 3: Evidence-Based Radiotherapy in Keloid Care – Part I

Jonathan Tsao, MD

Adjuvant Radiotherapy for the Treatment of Keloids.

Henry Weatherburn, PhD

A Data-Based Approach to a Keloid Post-Excisional Radiotherapy Treatment (PERT) Pathway.

John Glees, MD, FRCR, DMRT

Case Studies of Patient Outcomes of Re-Treatment of Recurrent Keloid Tumours by Fractionated Superficial X-Ray Radiotherapy

Zhongling Qiu, MD

Isotope Therapy to Prevent Post-Surgical Keloid Recurrence.

Fuquan Zhang, MD

Clinical Outcomes of Electronic Beam Irradiation for Post-Surgical Keloids in a Large-scale Investigation.

Panel Discussion and Q/A

12:30-13:30

Lunch Break

Special Session
12:40 - 13:00
Industry-Sponsored Presentations
TBD
Special Session
13:00 - 13:30
Keloid Research Foundation
Harmonizing Clinical Endpoints: Response Criteria Working Group for Keloid Trials
Session 3
13:30 - 15:00
Chair: Wei Liu, MD, PhD
Co-Chair: Henry Weatherburn, PhD
Clinical Session 4: Surgical Treatment of Keloids in Conjunction with Radiation Therapy

Jinglong Cai, PhD

TBD

Henry Weatherburn, PhD

A 15 Year Single Centre Audit of the Outcome of Fractionated Superficial X-Ray Radiotherapy Treatment of Recurrent Keloid Tumours.

Wei Liu, MD, PhD

Building up Multi-Level Defense Strategy for Post-Surgical Keloid Recurrence.

Xiaomei Han, MD

Full-Process Management of Auricular Keloids: The Role of the Innovative ABC Surgical Technique in a Multidisciplinary Treatment Framework.

Xiaodong Chen, MD, PhD

Nucleoresection Combined with Punch Extraction and Radiation Therapy: a Keloid Surgical Technique Worth Promoting.

Panel Discussion and Q/A

15:00 – 15:30

Coffee Break

Session 4

15:30 – 17:00

Chair: Xiaoli Wu, MD, PhD
Co-Chair: Michael Tirgan, MD
Clinical Research Session: Advances in Keloid Treatment Through Evidence-Based Studies

Qiqi Yin, MD

Current Practices in Keloid Treatment. A Survey of Dutch Dermatologists and Plastic Surgeons.

Qian-Yu Ma, MD, PhD

Laser combined with radiotherapy for keloid treatment: a novel and efficient comprehensive therapy with a lower recurrence rate.

Binrong Zhou, MD

Novel Needle-Type Electrocoagulation and Combination Pharmacotherapy: Basic and Clinical Studies on Efficacy and Safety in Treating Keloids.

Xiaoli Wu, MD, PhD

LCR Technique for Keloid Treatment

Wenbo Wang, MD, PhD

An Innovative Single-Stage Approach of High-Tension Keloid Excision and Reconstruction Using Acellular Dermal Matrix and Epidermal Skin Grafting.

Special Session

16:30-17:00

Lamont Jones, MD, MBA<br>

The Annual Jouni Uitto, MD, PhD International Visiting Professorship and Lecture in Molecular Dermatology<br>

Clinical Biomarkers: The Future of Keloid Disease’s Diagnosis and Treatment.

16:45 - 17:00
Panel Discussion and Q/A
Reception
17:00 - 18:30
Everyone is Invited
Dinner
19:30 - 22:30
Dinner for all attendees. Everyone is Invited

Time

Speaker

Title

DAY 3
Sunday June 8, 2025

08:30 - 09:00
Registration and Morning Coffee
Session 1
09:00 - 10:30
Chair: Michael H. Tirgan, MD
Co-Chair: Wei Liu, MD, PhD
Complexities in Keloid Disorder: Clinical Realities Across Age Groups

Michael H. Tirgan, MD

Pediatric Keloids: Case Review, Clinical Patterns, and Treatment Recommendations.

Xiqiao Wang, MD

Microbiome Dysbiosis Dominated by Rhodococcus Occurs in Keloids

Juliette Louter

How do I Deal with the Keloid Disease: a Qualitative Study Exploring Coping Strategies in a Multicultural Adult Patient Population.

Zhongyao Liang, MD, PhD

Linagliptin, a Potentially more Effective Drug for the Treatment of Keloids than 5-FU.

Zhehu Jin, MD, PhD

Real‑World Effectiveness and Safety of Bleomycin in Patients with Keloids and Hypertrophic Scars: a Systematic Review and Meta‑Analysis

Quqi Yin, MD

The Biodistribution of Triamcinolone Acetonide Injections in Severe Keloids, an Exploratory Three-Dimensional Fluorescent Cryomicrotome Study.

Yuting Huang, RN

Coping Tendencies Play a Partial Mediating Role between Social Support and Anxiety/Depression among Chinese Keloid Patients.

Panel Discussion and Q/A

10:30-10:45

Coffee Break

Session 2
10:45 - 12:30
Chair:
Co-Chair:
Abstract Presentation - Clinical Science

Cecilla Li, MD

Novel Concept and Clinical Practice of Keloid Pressure Therapy

Chunhui Xie, MD

Application of Core Excision in the Treatment of Keloids.

Yan Hao, MD

Clinical Observation of Subepidermal Vascular Network Flaps in Keloid Patients.

Bing Li, MD, PhD

Surgery Approaches and Experiences for Keloid Treatment and the Adjunctive Therapy.

Panel Discussion and Q/A

12:30-13:30

Lunch Break

Special Session
12:40 - 13:00
Industry-Sponsored Presentations
TBD
Special Session
13:00 - 13:30
Keloid Research Foundation
Bridging Progress: What We Learned in Shanghai and What Lies Ahead - Strategic Planning for Amsterdam 2026
Session 3
13:30 - 15:00
Chair: Frank Nissen, MD, PhD
Co-Chair: Lamont Jones, MD, PhD
Abstract Presentation - Basic Science

Akash Gunjan, PhD

Rationale Based Repurposing of FDA-Approved Agents for Keloid Management: An in Vitro Study.

Lian Zhang, MD

Integrated Multi-Omics Unveils the Epigenetic Landscape in the Pathogenesis of Keloid.

Chengcheng Deng, PhD

BMP2-Induced Adam12+ Fibroblasts Dictate Skin Scarring and Fibrosis.

Tianhao Li, PhD

TWIST1 Promote TGF-β Receptor I in Keloid Fibroblasts via Regulating the Stability of MEF2A.

Tianhao Li, PhD

Integrated Analysis of TWIST1 in Keloid Pathogenesis: Single-Cell Transcriptomics Reveals Fibroblast Heterogeneity and a Novel MEF2A-TBR1 Regulatory Axis.

Mengjie Shan, MD, PhD

Multi-Omics Analyses Reveal Bacteria and Catalase Associated with Keloid Disease.

Yixin Sun, MD, PhD

Single-Cell RNA Sequencing Revealed Key Factors of EMT to Promote Fibroblast Activation and Immune Infiltration in Keloid

Junxian Wen, PhD Candidate

Endothelial Dysfunction in Keloid Formation and Therapeutic Insights.

Lian Zhang, MD, PhD

Integrated Multi-Omics Unveils the Epigenetic Landscape in the Pathogenesis of Keloid.

Panel Discussion and Q/A

15:15 – 15:30

Coffee Break

Session 4

15:30 – 17:00

Chair: Wei Liu, MD, PhD
Co-Chair:
Abstract Presentation - Basic Science

Shuchen Gu, MD, PhD

Targeting the Nuclear Long Noncoding Transcript LSP1P5 Abrogates Extracellular Matrix Deposition by Trans-Upregulating CEBPA in Keloids.

Xinwen Kuang, MD, PhD candidate

Multi-Dimensional Effects of Hydrogen-Rich Materials on Wound Healing and Alleviating Skin Fibrosis.

Shuo Li, MD, PhD

Establishment of a Deep Learning-Based Automated Segmentation and Blood Perfusion Prediction System for Keloids.

Zhijin Li, PhD

Unraveling the Vascular Tapestry: Endothelial Dysfunction in Keloid Formation and Therapeutic Insights.

Ruoqing Xu, MBBS, PhD

ALKBH5-Mediated m6A Demethylation Ameliorates Extracellular Matrix Deposition in Cutaneous Pathological Fibrosis.

Ruoqing Xu, MBBS, PhD

ALKBH5-Mediated m6A Demethylation Ameliorates Extracellular Matrix Deposition in Cutaneous Pathological Fibrosis.

En Yang, MD, PhD

Single Cell Deciphering of Pruritic Keloids: the Interaction Between Fibroblasts and Schwann Cells Through the Midkine Signaling.

Yingrou Tan, PhD

Dual siRNAs Nanoplex Targeting IL-4RA and SPARC Enhance Collagen Reduction in IL-4 Activated Skin Fibroblasts.

Junxian Wen, MD

Insights from Comparing Blood Perfusion Metrics and Vancouver Scar Scale in Keloid Assessment.

Tu Liying, MD, PhD

ALKBH3-Mediated m1A Demethylation of METTL3 Endows Pathological Fibrosis: Interplay Between m1A and m6A RNA Methylation.

Panel Discussion and Q/A
Session 5

13:30 – 15:00

Chair: Michael Tirgan, MD
Co-Chair: Frank Nissen, MD, PhD
Parallel Session - Learnings from Patients - Clinical Behavior of Keloid Disorder

Michael H Tirgan, MD

Cartesian Model of Clinical Behavior of Keloid Disorder.

Session 5

15:30 – 16:30

Chair: Michael Tirgan, MD
Co-Chair: Frank Nissen, MD, PhD
Parallel Session - Non-Surgical Treatments - Case Studies

Michael H Tirgan, MD

Contact Cryotherapy in Treatment of Keloid Lesions, Indications and Case Studies.

16:45 - 17:00
Closing Remarks
Reception
17:00 - 18:30
Everyone is Invited