Master’s Degree in Dermatology (Year 2), Affiliated Hospital of Nantong University, Nantong, China.
Key Achievements:
- Co-First Author Publication:
“Nanozyme Microspheres with Structural Color-Coding Labels for Synergistic Therapy of Psoriasis” (APL Materials, IF: 4.24, 2024)
- Two poster presentations at the 13th Asian Dermatological Congress (13th ADC 2024)
- Oral Presentation “Bioinspired smart catalytic microneedle patch with structural color for infected wound management” at the 8th Annual Meeting of the Chinese Society for Investigative Dermatology (CSID 2024)
Abstract submitted for the 5th International Keloid Symposium
Title: Coping tendencies play partial mediating role between social support and anxiety/depression among Chinese keloid patients
AUTHORS: Yuting Huang1#, Shu Xu2#, Yuqi Wu1#,Zhifeng Gu3, Chen Dong4*, Li Zhang1*, Xiaodong Chen1*
AUTHORS’ AFFILIATIONS:
1 Department of Dermatology, Department of Nursing, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong 226001, China
2 School of Nursing and Rehabilitation, Nantong University, Affiliated Hospital of Nantong University, Nantong 226001, China
3 Department of Rheumatology, Research Center of Immunology, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong 226001, China
4 Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, Nantong 226001, China
Background: In addition to producing pain and itching, keloids can cause psychological symptoms, including anxiety and depression. We aimed to investigate the prevalence and underlying factors of anxiety/depression in Chinese keloid patients and to explore the mediating role between social support and anxiety/depression.
Methods: A total of 202 self-reported questionnaires were collected from keloid patients, including the General Information Questionnaire, Vancouver Scar Assessment Scale (VSS), Patient and Observer Scar Assessment Scale (POSAS), Dermatological Problems Quality of Life Inventory (DLQI), Social Support Rating Scale (SSRS), Simple Coping Styles Scale (SCSQ), Self-Efficacy Scale (GSES) and the Heart Attitude Assessment (HADS).
Results: The mean scores for anxiety and depression were 9.82±2.20 and 7.96±2.70, respectively. Annual income (OR=0.258), GSES score (OR=0.2955), pain symptoms (OR=1.281) and coping styles (OR:3.321) were significantly associated with HADS anxiety in keloid patients (P<0.05), whereas use of support (OR=0.607) was significantly associated with HADS depression in keloid patients (p<0.05). The area under the curve (AUC) for the combined anxiety ROC for annual income, coping styles, pain symptoms and GSES scores was 0.835. PROCESS analysis concluded that coping tendencies partially mediated the relationship between social support and depression, with the mediating effect accounting for 38.58% of the total effect.
Conclusion: Coping tendency in keloid patients played a partial mediating role between social support and depression. Future studies should further explore how training in coping tendencies can enhance the effectiveness of social support to more effectively prevent and reduce depressive symptoms.
