EDUCATION:
| 2004-2009 | Bachelor, M.D. | Fourth Military Medical University, Xi’an, China |
| 2009-2012 | Master, Plastic Surgery | Xijing Hospital, Xi’an, China |
| 2012-2016 | Ph.D, Dermatology | Xijing Hospital, Xi’an, China |
CLINICAL EXPERIENCE
| 2016-2018 | Resident physician | Dep. of Dermatology, Xijing Hospital, Xian, China |
| 2018-2019 | Chief Resident | Dep. of Dermatology, Xijing Hospital, Xian, China |
| 2019-2021 | Consultant | Dep. of Dermatology, Xijing Hospital, Xian, China |
| 2021- | Associate Chief Physician | Dep. of Dermatology, Xijing Hospital, Xian, China |
AWARDS AND HONORS:
2020, First prize, Emerging educators engaged in educational competitions, Chinese Society of Dermatology.
2021, Second prize(Rank Fourth), Science and Technology Progress Award, Ministry of Education of the People’s Republic of China.
2022, First prize(Rank Fourth), Medical Research Innovation Award, Chinese Research Hospital Association.
RESEARCH FUNDING:
2016 National Natural Science Foundation of China (Youth Investigator Program) No. 81600281
2021 National Natural Science Foundation of China(General Program) No. 82073435
ACADEMIC PARTICIPATION:
Shannxi Anti-cancer Association, Skin Tumor Branch, Standing Committee
Chinese Society of Dermatology, Group of Hypertropic Scar and Keloid, Committee
Shannxi Medical Association,Branch of Dermatology and Venereology, Committee
Medical Reference, Channel of Dermatology and venereology, Young Editorial Board
EXPERIENCES:
I am engaged in the clinical work of scar therapy using surgery, laser, and injection, and the basic research and clinical work in psoriasis and skin immunology. As the leader of scar group in the department of dermatology of Xijing hospital, we performed micro-punch combined with electronic wiree electron beam radiation for keloid treatment, SVF-gel injection for acne scar treatment.
PUBLICATIONS
First and co-first authorship
1.Bing Li*, Jie Lei*, Luting Yang*, Chao Gao, Erle Dang, Tianyu Cao, Ke Xue, Yuchen Zhuang, Shuai Shao, Dalong Zhi, Junfeng Hao, Liang Jin, Pei Qiao, Weiming Ouyang and Gang Wang. Dysregulation of Akt-FOXO1 Pathway Leads to Dysfunction of Regulatory T Cells in Patients with Psoriasis. Journal of Investigative Dermatology. 2019. 139(10):2098-2107.
2.Yiting Lin*, Ke Xue*, Qingyang Li*, Zhenhua Liu, Zhenlai Zhu, Jiaoling Chen, Erle Dang, Lei Wang, Weigang Zhang, Gang Wang#, Bing Li#. Cyclin-dependent kinase 7 promotes Th17/Th1 cell differentiation in psoriasis by modulating glycolytic metabolism. Journal of Investigative Dermatology. 2021.54(2):139-142
3.Yiting Lin*, Weigang Zhang, Bing Li#, Gang Wang#. Keratin17 in psoriasis: Current understanding and future perspective. Seminar in Cell and Developmental Biology.2021, S1084-9521(21): 00169-54.Yixin Luo*, Bingyu Pang*, Junfeng Hao*, Qingyang Li, Pei Qiao, Chen Zhang, Yaxing Bai, Chunying Xiao, Jiaoling Chen, Dalong Zhi, Ying Liu, Erle Dang, Gang Wang#, Bing Li#. Keratin17 covalently binds to alpha-enolase and exacerbates proliferation of keratinocytes in psoriasis. International Journal of Biological Sciences. 2023; 19(11): 3395-3411.
5.Bing Li*, Chao Gao*, Jiansheng Diao, Dalei Wang, Feifei Chu, Yang Li, Gang Wang, Shuzhong Guo, Wei Xia. Aberrant Notch signalling contributes to hypertrophic scar formation by modulating the phenotype of keratinocytes. Experimental Dermatology. 2016. 25(2):137-142.
6.ZhangYangyang*, Lin Yiting*, Wang Lei*, Sun Xiuwen, Dang Erle, Xue Ke, Zhang Weigang, Zhang Kaiming, Wang Gang#, and Li Bing#. CD8αα+T cells exert a pro‐inflammatory role in patients with psoriasis. Skin Health and Disease 2021, 1(4).
7.Chao Gao*, Rutao Wang*, Bing Li*, Yongzhen Guo, Tao Yin, Yunlong Xia, Fuyang Zhang, Kun Lian, Yi Liu, Han Wang, Ling Zhang, Erhe Gao, Wenjun Yan, Ling Tao. TXNIP/Redd1 signalling and excessive autophagy: a novel mechanism of myocardial ischaemia/ reperfusion injury in mice. Cardiovascular Research. 2020.116: 645-657.
8.Weigang Zhang*, Sen Guo*, Bing Li*, Lin Liu, Rui Ge, Tianyu Cao, Huina Wang, Tianwen Gao, Gang Wang, Chunying Li. Proinammatory effect of high-mobility group protein B1 on keratinocytes: an autocrine mechanism underlying psoriasis development. Journal of Pathology. 2017. 241(3):392-404.
9.Luting Yang*, Bing Li*, Erle Dang, Liang Jin, Xueli Fan, Gang Wang. Impaired function of regulatory T cells in patients with psoriasis is mediated by phosphorylation of STAT3. Journal of Dermatological Science. 2016. 81(2):85-92.
10.Zhenfeng Liu*, Erle Dang*, Bing Li*, Hongjiang Qiao, Liang Jin, Jieyu Zhang, Gang Wang. Dysfunction of CD19+CD24hiCD27+ B regulatory cells in patients with bullous pemphigoid. Scientific Report. 2018. 8:703.
11.Tianyu Cao*, Shuai Shao*, Bing Li*, Liang Jin, Jie Lei, Hongjiang Qiao, Gang Wang. Up-regulation of Interferon-inducible protein 16 contributes to psoriasis by modulating chemokine production in keratinocytes. Scientific Report. 2016. 6:25381.
12.Man Jiang*, Bing Li*, Jieyu Zhang, Lei Hu, Erle Dang, Gang Wang. Vascular endothelial growth factor driving aberrant keratin expression pattern contributes to the pathogenesis of psoriasis. Experimental Cell Research. 2017. 360(2):310-319.
13.Yuchen Zhuang*, Changxu Han*, Bing Li*, Liang Jin, Erle Dang, Hui Fang, Hongjiang Qiao, Gang Wang. NB-UVB irradiation downregulates keratin-17 expression in keratinocytes by inhibiting the ERK1/2 and STAT3 signaling pathways. Archives of Dermatological Research. 2018. 310:147-156.
Abstract submitted for the 5th International Keloid Symposium
Keloid is a type of pathological scars characterized by excessive activity of fibroblast and redundant deposition of extracellular matrix. It always caused by trauma, acne, folliculitis and some unknown reasons. The current treatments for keloid include surgical resection and local corticosteroid injections. The high rates of recurrence is still an challenge. Current recommendations and consensus suggest that the selection of a treatment strategy should be determined by the size of the keloid. The diameter less than 2cm can be treated with local corticosteroid injections. The diameter more than 2cm can be treated with surgical excision combined with radiotherapy. However, patient with scattered and multiple lesions is a big challenge. We provides some cases with keloids that choice of surgical method is determined by the anatomic site and the appearance of lesions. The first choice for larger keloid on the ear is core excision to maintain the shape of the auricles. The large keloid on lower jaw or trunk is often originate from acne and folliculitis, and the choice of surgical method is determined by JSW scar scale (JSS), the growth pattern and the surface of lesion. When the JSS score of elevation is 3, and the lesional surface is rough, it is best to perform excision, and followed by low tension primary sutures, skin grafts or flaps to close the wound. If the lesional surface is smooth and the border within the wound, we first choose core excision. However, if the lesional surface is smooth but the border beyond the wound, we perform excision and close the wound by skin grafts from the keloid. In cases where multiple keloids are dispersed and exhibit partial confluence, a micro-punch technique is employed for lesions that have a JSS elevation score of less than 3. Conversely, core excision is indicated for lesions with a JSS elevation score of 3. Electron beam irradiation is performed within 24 hours after the surgery. Then compression therapy , injection and 595-nm pulsed dye laser can be chose as adjuvant treatment. Now, we will present some cases to provide our experience on keloid treatment.
