Dorothy Supp, PhD

Dorothy SuppResearch Professor (Adjunct); Investigator, Shriners Hospitals for Children – Cincinnati

Dr. Supp is Senior Investigator at the Shriners Hospitals for Children, Cincinnati Burns Hospital. She also holds an adjunct appointment as a Research Professor in the Department of Surgery at the University of Cincinnati, College of Medicine. She earned her bachelor’s degree from Cornell University and her PhD in Developmental Biology from the University of Cincinnati. After postdoctoral training in Dr. Steven Potter’s lab at the Cincinnati Children’s Hospital Research Foundation, where she cloned the gene responsible for establishing left-right axis asymmetry, she was awarded a fellowship to study skin tissue engineering in Dr. Steven Boyce’s laboratory at the Shriners Burns Institute.

Dr. Supp’s research focuses on wound healing, including development of next-generation skin substitutes and understanding the molecular basis for keloid and hypertrophic scarring. She developed an organotypic model for testing keloid suppression strategies based on engineered skin substitutes, generated using keloid-derived cells and grafted to mice. She is particularly interested in the role of keratinocytes in regulation of keloid pathology. Her laboratory is funded by the Shriners Hospitals for Children, with additional support from the NIH and US Department of Defense. She is on the editorial boards of the journals Burns and the Journal of Burn Care and Research.