Melissa B. Davis, PhD
Dr. Melissa B Davis, Ph.D. is an Assistant Scientist in the Population Health Division of the Henry Ford Health System’s Cancer Institute. Dr. Davis received her Ph.D. at the University of Georgia (Athens, GA, USA) in molecular genetics where she completed groundbreaking work indicating the functional distinctions of steroid hormone transcript/protein isoforms during development. This led to her genomics and systems biology training at Yale School of Medicine (New Haven, CT, USA) where her work on tissue-specific hormone receptor function was embedded in the large consortia effort, the modEncode project.
Dr. Davis also completed post-doctoral training at the Center for Interdisciplinary Health Disparities at the University of Chicago where she began her current research interest, to identify biological mechanisms of race-related disparities in cancer. The Davis lab has produced findings that establish a unique genetic signature in breast and prostate tumors of African and African American patients highlighting mechanisms of tumor progression that will extend opportunities for precision medicine in minority populations.
Her current work builds upon findings in her breast cancer research, where she has identified that the tumor expression of a chemokine receptor (ACKR1) is linked to the tumor-specific immune/inflammatory response. In the context of keloids, Dr. Davis is now investigating whether the expression of ACKR1 in keloids is also linked to a distinct inflammatory response.